First Incarnation (AppSnapp)
Initially, Conceited Software utilized the LibTiff exploit with jailbreakme.com, which also went by the name "AppSnapp," to jailbreak iOS 1.1.1. Upon the release of iOS 2.0 and the debut of the App Store, Conceited Software closed JailbreakMe, when it remained dormant for a while.
Second Incarnation (Star)
Main article: Star
comex has since repurposed the domain for Star, his userland jailbreak for iOS 3.1.2 through 4.0.1. However, comex stated that the bug used for the untethered jailbreak was there until 4.3 as Apple did not patch the bug correctly. It was properly patched on 4.3.1 in order to prevent the jailbreak of the iPad 2. It's still possible the site could be repurposed to jailbreak iDevices up to 4.3, but this has not yet been done.
Third Incarnation (Saffron)
Main article: Saffron
In June 2011, comex began to put up teasers on JailbreakMe. In early July 2011, someone Googled comex's other site and found a prerelease version of "Saffron," the third incarnation of JailbreakMe. Word about this "leak" inevitably spread. On July 6, 2011, "Saffron" made its official debut on JailbreakMe.
On October 7, 2011, MuscleNerd announced that the domain was sold and that the new owner was unknown, so that there is a big danger of the site hosting malware. It turned out that the new owner was friendly and sold it the next day to Saurik who hosted the site anyway. Problem solved.